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congenital amputation : ウィキペディア英語版
congenital amputation

Congenital amputation is birth without a limb or limbs, or without a part of a limb or limbs.
It is known to be caused by blood clots forming in the fetus while ''in utero'' (vascular insult) and from amniotic band syndrome: fibrous bands of the amnion that constrict foetal limbs to such an extent that they fail to form or actually fall off due to missing blood supply. Congenital amputation can also occur due to maternal exposure to teratogens during pregnancy.
==Description==
Congenital amputation is the least common reason for amputation, but it is projected that one in 2000 babies are born each year with a missing or deformed limb. During certain periods in history, an increase in congenital amputations has been documented. One example includes the thalidomide tragedy that occurred in the 1960s when pregnant mothers were given a tranquilizer that contained the harmful drug, which produced an increase in children born without limbs. Another example was the Chernobyl catastrophe in Russia, where the radiation exposure caused many children to be born with abnormal or missing limbs.

抄文引用元・出典: フリー百科事典『 ウィキペディア(Wikipedia)
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